Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis

• Congenital human cytomegalovirus (CMV) infection causes severe neuropathogenesis. • Murine CMV failed to break through the placental barrier to transmit to fetus. • Zhou et al. established a novel mouse system to model congenital HCMV infection. • The mouse CMV system by Zhou et al can be used for...

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Detalles Bibliográficos
Autores principales: Armstrong, Najealicka, Tang, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170950/
https://www.ncbi.nlm.nih.gov/pubmed/35504536
http://dx.doi.org/10.1016/j.virs.2022.04.007
Descripción
Sumario:• Congenital human cytomegalovirus (CMV) infection causes severe neuropathogenesis. • Murine CMV failed to break through the placental barrier to transmit to fetus. • Zhou et al. established a novel mouse system to model congenital HCMV infection. • The mouse CMV system by Zhou et al can be used for drug screening.

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