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Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis
• Congenital human cytomegalovirus (CMV) infection causes severe neuropathogenesis. • Murine CMV failed to break through the placental barrier to transmit to fetus. • Zhou et al. established a novel mouse system to model congenital HCMV infection. • The mouse CMV system by Zhou et al can be used for...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wuhan Institute of Virology, Chinese Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170950/ https://www.ncbi.nlm.nih.gov/pubmed/35504536 http://dx.doi.org/10.1016/j.virs.2022.04.007 |
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author | Armstrong, Najealicka Tang, Qiyi |
author_facet | Armstrong, Najealicka Tang, Qiyi |
author_sort | Armstrong, Najealicka |
collection | PubMed |
description | • Congenital human cytomegalovirus (CMV) infection causes severe neuropathogenesis. • Murine CMV failed to break through the placental barrier to transmit to fetus. • Zhou et al. established a novel mouse system to model congenital HCMV infection. • The mouse CMV system by Zhou et al can be used for drug screening. |
format | Online Article Text |
id | pubmed-9170950 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wuhan Institute of Virology, Chinese Academy of Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-91709502022-06-08 Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis Armstrong, Najealicka Tang, Qiyi Virol Sin Perspective • Congenital human cytomegalovirus (CMV) infection causes severe neuropathogenesis. • Murine CMV failed to break through the placental barrier to transmit to fetus. • Zhou et al. established a novel mouse system to model congenital HCMV infection. • The mouse CMV system by Zhou et al can be used for drug screening. Wuhan Institute of Virology, Chinese Academy of Sciences 2022-05-02 /pmc/articles/PMC9170950/ /pubmed/35504536 http://dx.doi.org/10.1016/j.virs.2022.04.007 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Perspective Armstrong, Najealicka Tang, Qiyi Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
title | Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
title_full | Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
title_fullStr | Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
title_full_unstemmed | Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
title_short | Congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
title_sort | congenital cytomegalovirus infection and advances in murine models of neuropathogenesis |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170950/ https://www.ncbi.nlm.nih.gov/pubmed/35504536 http://dx.doi.org/10.1016/j.virs.2022.04.007 |
work_keys_str_mv | AT armstrongnajealicka congenitalcytomegalovirusinfectionandadvancesinmurinemodelsofneuropathogenesis AT tangqiyi congenitalcytomegalovirusinfectionandadvancesinmurinemodelsofneuropathogenesis |