Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection

• The N-terminal tail of histone H3 is specifically cleaved during EV71 infection. • Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail. • Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interacti...

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Detalles Bibliográficos
Autores principales: Miao, Meng, Deng, Gang, Xiong, Xiaobei, Qiu, Yang, Huang, Wenda, Yuan, Meng, Yu, Fei, Bai, Shimei, Zhou, Xi, Zhao, Xiaolu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170973/
https://www.ncbi.nlm.nih.gov/pubmed/35256288
http://dx.doi.org/10.1016/j.virs.2022.02.006
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author Miao, Meng
Deng, Gang
Xiong, Xiaobei
Qiu, Yang
Huang, Wenda
Yuan, Meng
Yu, Fei
Bai, Shimei
Zhou, Xi
Zhao, Xiaolu
author_facet Miao, Meng
Deng, Gang
Xiong, Xiaobei
Qiu, Yang
Huang, Wenda
Yuan, Meng
Yu, Fei
Bai, Shimei
Zhou, Xi
Zhao, Xiaolu
author_sort Miao, Meng
collection PubMed
description • The N-terminal tail of histone H3 is specifically cleaved during EV71 infection. • Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail. • Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions.
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spelling pubmed-91709732022-06-08 Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection Miao, Meng Deng, Gang Xiong, Xiaobei Qiu, Yang Huang, Wenda Yuan, Meng Yu, Fei Bai, Shimei Zhou, Xi Zhao, Xiaolu Virol Sin Letter • The N-terminal tail of histone H3 is specifically cleaved during EV71 infection. • Viral protease 3C is identified as a protease responsible for proteolytically processing the N-terminal H3 tail. • Our finding reveals a new epigenetic regulatory mechanism for Enterovirus 71 in virus-host interactions. Wuhan Institute of Virology, Chinese Academy of Sciences 2022-02-18 /pmc/articles/PMC9170973/ /pubmed/35256288 http://dx.doi.org/10.1016/j.virs.2022.02.006 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letter
Miao, Meng
Deng, Gang
Xiong, Xiaobei
Qiu, Yang
Huang, Wenda
Yuan, Meng
Yu, Fei
Bai, Shimei
Zhou, Xi
Zhao, Xiaolu
Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection
title Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection
title_full Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection
title_fullStr Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection
title_full_unstemmed Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection
title_short Enterovirus 71 3C proteolytically processes the histone H3 N-terminal tail during infection
title_sort enterovirus 71 3c proteolytically processes the histone h3 n-terminal tail during infection
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170973/
https://www.ncbi.nlm.nih.gov/pubmed/35256288
http://dx.doi.org/10.1016/j.virs.2022.02.006
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