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Post-Translational Modifications of p53 in Ferroptosis: Novel Pharmacological Targets for Cancer Therapy

The tumor suppressor p53 is a well-known cellular guardian of genomic integrity that blocks cell cycle progression or induces apoptosis upon exposure to cellular stresses. However, it is unclear how the remaining activities of p53 are regulated after the abrogation of these routine activities. Ferro...

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Detalles Bibliográficos
Autores principales: Zhang, Le, Hou, Ningning, Chen, Bing, Kan, Chengxia, Han, Fang, Zhang, Jingwen, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171069/
https://www.ncbi.nlm.nih.gov/pubmed/35685623
http://dx.doi.org/10.3389/fphar.2022.908772

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