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Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia

Unlike classic pyoderma gangrenosum (PG), the bullous variant of PG is typically represented by a painful erythematous papule, plaque, and superficial bulla that progress into the ulceration with bullous margin. Generally, bullous PG is most commonly associated with myeloproliferative disorders, suc...

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Autores principales: Kwon, Chang-Il, Lee, Gyeong-Won, Kim, Chi-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171183/
https://www.ncbi.nlm.nih.gov/pubmed/35721340
http://dx.doi.org/10.5021/ad.2022.34.3.212
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author Kwon, Chang-Il
Lee, Gyeong-Won
Kim, Chi-Yeon
author_facet Kwon, Chang-Il
Lee, Gyeong-Won
Kim, Chi-Yeon
author_sort Kwon, Chang-Il
collection PubMed
description Unlike classic pyoderma gangrenosum (PG), the bullous variant of PG is typically represented by a painful erythematous papule, plaque, and superficial bulla that progress into the ulceration with bullous margin. Generally, bullous PG is most commonly associated with myeloproliferative disorders, such as acute myeloid leukemia (AML). Bullous PG in AML patients rarely occurs, but once it does, it suggests a poor clinical prognosis. Although many cases of classic PG in AML patients have been reported, bullous PG is relatively rare. Therefore, we present a case of bullous PG that developed in a patient with AML and was successfully treated with high-dose systemic steroids.
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spelling pubmed-91711832022-06-17 Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia Kwon, Chang-Il Lee, Gyeong-Won Kim, Chi-Yeon Ann Dermatol Case Report Unlike classic pyoderma gangrenosum (PG), the bullous variant of PG is typically represented by a painful erythematous papule, plaque, and superficial bulla that progress into the ulceration with bullous margin. Generally, bullous PG is most commonly associated with myeloproliferative disorders, such as acute myeloid leukemia (AML). Bullous PG in AML patients rarely occurs, but once it does, it suggests a poor clinical prognosis. Although many cases of classic PG in AML patients have been reported, bullous PG is relatively rare. Therefore, we present a case of bullous PG that developed in a patient with AML and was successfully treated with high-dose systemic steroids. The Korean Dermatological Association; The Korean Society for Investigative Dermatology 2022-06 2022-05-20 /pmc/articles/PMC9171183/ /pubmed/35721340 http://dx.doi.org/10.5021/ad.2022.34.3.212 Text en Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kwon, Chang-Il
Lee, Gyeong-Won
Kim, Chi-Yeon
Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
title Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
title_full Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
title_fullStr Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
title_full_unstemmed Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
title_short Bullous Variant of Pyoderma Gangrenosum in a Patient with Acute Myeloid Leukemia
title_sort bullous variant of pyoderma gangrenosum in a patient with acute myeloid leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171183/
https://www.ncbi.nlm.nih.gov/pubmed/35721340
http://dx.doi.org/10.5021/ad.2022.34.3.212
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