Cargando…
Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report
Postpolio syndrome (PPS) is widely known to manifest as muscle weakness in patients affected by poliomyelitis in early childhood. This is caused by the long-term overwork of motor nerves regenerated from surviving nerve cells. We report a characteristic delay in recovery from muscle relaxation after...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Dental Society of Anesthsiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171338/ https://www.ncbi.nlm.nih.gov/pubmed/35693355 http://dx.doi.org/10.17245/jdapm.2022.22.3.233 |
_version_ | 1784721643831033856 |
---|---|
author | Kimura, Yukifumi Nitta, Yukie Shibuya, Makiko Fujisawa, Toshiaki |
author_facet | Kimura, Yukifumi Nitta, Yukie Shibuya, Makiko Fujisawa, Toshiaki |
author_sort | Kimura, Yukifumi |
collection | PubMed |
description | Postpolio syndrome (PPS) is widely known to manifest as muscle weakness in patients affected by poliomyelitis in early childhood. This is caused by the long-term overwork of motor nerves regenerated from surviving nerve cells. We report a characteristic delay in recovery from muscle relaxation after administering rocuronium to a patient with PPS under general anesthesia with desflurane. A 59-year-old woman was scheduled to undergo surgical debridement for jaw osteonecrosis. She had a history of poliomyelitis at the age of 2 years, and was diagnosed with PPS at the age of 51 years. General anesthesia was induced with 80 mg propofol, 50 µg fentanyl, and 30 mg (0.69 mg/kg) rocuronium, and maintained with desflurane and remifentanil. The durations of train-of-four (TOF) count 0 and 1 were 96 and 37 min, respectively. Five minutes after discontinuing desflurane, the TOF count was 4. Three minutes after administering 200 mg sugammadex, the TOF ratio was 0.83, and the tracheal tube was subsequently removed. In summary, the effect of a single dose of rocuronium on twitch in TOF monitoring was significantly prolonged in a patient with PPS, which may have been exacerbated by desflurane. |
format | Online Article Text |
id | pubmed-9171338 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Korean Dental Society of Anesthsiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-91713382022-06-10 Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report Kimura, Yukifumi Nitta, Yukie Shibuya, Makiko Fujisawa, Toshiaki J Dent Anesth Pain Med Case Report Postpolio syndrome (PPS) is widely known to manifest as muscle weakness in patients affected by poliomyelitis in early childhood. This is caused by the long-term overwork of motor nerves regenerated from surviving nerve cells. We report a characteristic delay in recovery from muscle relaxation after administering rocuronium to a patient with PPS under general anesthesia with desflurane. A 59-year-old woman was scheduled to undergo surgical debridement for jaw osteonecrosis. She had a history of poliomyelitis at the age of 2 years, and was diagnosed with PPS at the age of 51 years. General anesthesia was induced with 80 mg propofol, 50 µg fentanyl, and 30 mg (0.69 mg/kg) rocuronium, and maintained with desflurane and remifentanil. The durations of train-of-four (TOF) count 0 and 1 were 96 and 37 min, respectively. Five minutes after discontinuing desflurane, the TOF count was 4. Three minutes after administering 200 mg sugammadex, the TOF ratio was 0.83, and the tracheal tube was subsequently removed. In summary, the effect of a single dose of rocuronium on twitch in TOF monitoring was significantly prolonged in a patient with PPS, which may have been exacerbated by desflurane. The Korean Dental Society of Anesthsiology 2022-06 2022-05-27 /pmc/articles/PMC9171338/ /pubmed/35693355 http://dx.doi.org/10.17245/jdapm.2022.22.3.233 Text en Copyright © 2022 Journal of Dental Anesthesia and Pain Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kimura, Yukifumi Nitta, Yukie Shibuya, Makiko Fujisawa, Toshiaki Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
title | Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
title_full | Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
title_fullStr | Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
title_full_unstemmed | Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
title_short | Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
title_sort | prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171338/ https://www.ncbi.nlm.nih.gov/pubmed/35693355 http://dx.doi.org/10.17245/jdapm.2022.22.3.233 |
work_keys_str_mv | AT kimurayukifumi prolongationoftheeffectofasingledoseofrocuroniuminapatientwithpostpoliosyndromeunderdesfluraneanesthesiaacasereport AT nittayukie prolongationoftheeffectofasingledoseofrocuroniuminapatientwithpostpoliosyndromeunderdesfluraneanesthesiaacasereport AT shibuyamakiko prolongationoftheeffectofasingledoseofrocuroniuminapatientwithpostpoliosyndromeunderdesfluraneanesthesiaacasereport AT fujisawatoshiaki prolongationoftheeffectofasingledoseofrocuroniuminapatientwithpostpoliosyndromeunderdesfluraneanesthesiaacasereport |