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CRISPR-Cas technology a new era in genomic engineering

The CRISPR-Cas systems have offered a flexible, easy-to-use platform to precisely modify and control the genomes of organisms in various fields, ranging from agricultural biotechnology to therapeutics. This system is extensively used in the study of infectious, progressive, and life-threatening gene...

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Detalles Bibliográficos
Autores principales: Parsaeimehr, Ali, Ebirim, Rosemary I., Ozbay, Gulnihal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171425/
https://www.ncbi.nlm.nih.gov/pubmed/35686011
http://dx.doi.org/10.1016/j.btre.2022.e00731
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author Parsaeimehr, Ali
Ebirim, Rosemary I.
Ozbay, Gulnihal
author_facet Parsaeimehr, Ali
Ebirim, Rosemary I.
Ozbay, Gulnihal
author_sort Parsaeimehr, Ali
collection PubMed
description The CRISPR-Cas systems have offered a flexible, easy-to-use platform to precisely modify and control the genomes of organisms in various fields, ranging from agricultural biotechnology to therapeutics. This system is extensively used in the study of infectious, progressive, and life-threatening genetic diseases for the improvement of quality and quantity of major crops and in the development of sustainable methods for the generation of biofuels. As CRISPR-Cas technology continues to evolve, it is becoming more controllable and precise with the addition of molecular regulators, which will provide benefits for everyone and save many lives. Studies on the constant growth of CRISPR technology are important due to its rapid development. In this paper, we present the current applications and progress of CRISPR-Cas genome editing systems in several fields of research, we further highlight the applications of anti-CRISPR molecules to regulate CRISPR-Cas gene editing systems, and we discuss ethical considerations in CRISPR-Cas applications.
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spelling pubmed-91714252022-06-08 CRISPR-Cas technology a new era in genomic engineering Parsaeimehr, Ali Ebirim, Rosemary I. Ozbay, Gulnihal Biotechnol Rep (Amst) Review Article The CRISPR-Cas systems have offered a flexible, easy-to-use platform to precisely modify and control the genomes of organisms in various fields, ranging from agricultural biotechnology to therapeutics. This system is extensively used in the study of infectious, progressive, and life-threatening genetic diseases for the improvement of quality and quantity of major crops and in the development of sustainable methods for the generation of biofuels. As CRISPR-Cas technology continues to evolve, it is becoming more controllable and precise with the addition of molecular regulators, which will provide benefits for everyone and save many lives. Studies on the constant growth of CRISPR technology are important due to its rapid development. In this paper, we present the current applications and progress of CRISPR-Cas genome editing systems in several fields of research, we further highlight the applications of anti-CRISPR molecules to regulate CRISPR-Cas gene editing systems, and we discuss ethical considerations in CRISPR-Cas applications. Elsevier 2022-04-12 /pmc/articles/PMC9171425/ /pubmed/35686011 http://dx.doi.org/10.1016/j.btre.2022.e00731 Text en © 2022 The Author(s). Published by Elsevier B.V. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Parsaeimehr, Ali
Ebirim, Rosemary I.
Ozbay, Gulnihal
CRISPR-Cas technology a new era in genomic engineering
title CRISPR-Cas technology a new era in genomic engineering
title_full CRISPR-Cas technology a new era in genomic engineering
title_fullStr CRISPR-Cas technology a new era in genomic engineering
title_full_unstemmed CRISPR-Cas technology a new era in genomic engineering
title_short CRISPR-Cas technology a new era in genomic engineering
title_sort crispr-cas technology a new era in genomic engineering
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171425/
https://www.ncbi.nlm.nih.gov/pubmed/35686011
http://dx.doi.org/10.1016/j.btre.2022.e00731
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