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CRISPR-Cas technology a new era in genomic engineering
The CRISPR-Cas systems have offered a flexible, easy-to-use platform to precisely modify and control the genomes of organisms in various fields, ranging from agricultural biotechnology to therapeutics. This system is extensively used in the study of infectious, progressive, and life-threatening gene...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171425/ https://www.ncbi.nlm.nih.gov/pubmed/35686011 http://dx.doi.org/10.1016/j.btre.2022.e00731 |
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author | Parsaeimehr, Ali Ebirim, Rosemary I. Ozbay, Gulnihal |
author_facet | Parsaeimehr, Ali Ebirim, Rosemary I. Ozbay, Gulnihal |
author_sort | Parsaeimehr, Ali |
collection | PubMed |
description | The CRISPR-Cas systems have offered a flexible, easy-to-use platform to precisely modify and control the genomes of organisms in various fields, ranging from agricultural biotechnology to therapeutics. This system is extensively used in the study of infectious, progressive, and life-threatening genetic diseases for the improvement of quality and quantity of major crops and in the development of sustainable methods for the generation of biofuels. As CRISPR-Cas technology continues to evolve, it is becoming more controllable and precise with the addition of molecular regulators, which will provide benefits for everyone and save many lives. Studies on the constant growth of CRISPR technology are important due to its rapid development. In this paper, we present the current applications and progress of CRISPR-Cas genome editing systems in several fields of research, we further highlight the applications of anti-CRISPR molecules to regulate CRISPR-Cas gene editing systems, and we discuss ethical considerations in CRISPR-Cas applications. |
format | Online Article Text |
id | pubmed-9171425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91714252022-06-08 CRISPR-Cas technology a new era in genomic engineering Parsaeimehr, Ali Ebirim, Rosemary I. Ozbay, Gulnihal Biotechnol Rep (Amst) Review Article The CRISPR-Cas systems have offered a flexible, easy-to-use platform to precisely modify and control the genomes of organisms in various fields, ranging from agricultural biotechnology to therapeutics. This system is extensively used in the study of infectious, progressive, and life-threatening genetic diseases for the improvement of quality and quantity of major crops and in the development of sustainable methods for the generation of biofuels. As CRISPR-Cas technology continues to evolve, it is becoming more controllable and precise with the addition of molecular regulators, which will provide benefits for everyone and save many lives. Studies on the constant growth of CRISPR technology are important due to its rapid development. In this paper, we present the current applications and progress of CRISPR-Cas genome editing systems in several fields of research, we further highlight the applications of anti-CRISPR molecules to regulate CRISPR-Cas gene editing systems, and we discuss ethical considerations in CRISPR-Cas applications. Elsevier 2022-04-12 /pmc/articles/PMC9171425/ /pubmed/35686011 http://dx.doi.org/10.1016/j.btre.2022.e00731 Text en © 2022 The Author(s). Published by Elsevier B.V. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Article Parsaeimehr, Ali Ebirim, Rosemary I. Ozbay, Gulnihal CRISPR-Cas technology a new era in genomic engineering |
title | CRISPR-Cas technology a new era in genomic engineering |
title_full | CRISPR-Cas technology a new era in genomic engineering |
title_fullStr | CRISPR-Cas technology a new era in genomic engineering |
title_full_unstemmed | CRISPR-Cas technology a new era in genomic engineering |
title_short | CRISPR-Cas technology a new era in genomic engineering |
title_sort | crispr-cas technology a new era in genomic engineering |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171425/ https://www.ncbi.nlm.nih.gov/pubmed/35686011 http://dx.doi.org/10.1016/j.btre.2022.e00731 |
work_keys_str_mv | AT parsaeimehrali crisprcastechnologyaneweraingenomicengineering AT ebirimrosemaryi crisprcastechnologyaneweraingenomicengineering AT ozbaygulnihal crisprcastechnologyaneweraingenomicengineering |