TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect G(q/11)–G(i/o) coincidence signals of variable strengths

Transient receptor potential canonical 4 (TRPC4) is a receptor-operated cation channel codependent on both the G(q/11)–phospholipase C signaling pathway and G(i/o) proteins for activation. This makes TRPC4 an excellent coincidence sensor of neurotransmission through G(q/11)- and G(i/o)-coupled recep...

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Detalles Bibliográficos
Autores principales: Tian, Jin-bin, Yang, Jane, Joslin, William C., Flockerzi, Veit, Prescott, Steven A., Birnbaumer, Lutz, Zhu, Michael X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171772/
https://www.ncbi.nlm.nih.gov/pubmed/35544691
http://dx.doi.org/10.1073/pnas.2120870119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171772/
https://www.ncbi.nlm.nih.gov/pubmed/35544691
http://dx.doi.org/10.1073/pnas.2120870119

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