Cargando…
Synaptotagmin-1 is a bidirectional Ca(2+) sensor for neuronal endocytosis
Exocytosis and endocytosis are tightly coupled. In addition to initiating exocytosis, Ca(2+) plays critical roles in exocytosis–endocytosis coupling in neurons and nonneuronal cells. Both positive and negative roles of Ca(2+) in endocytosis have been reported; however, Ca(2+) inhibition in endocytos...
Autores principales: | Chen, Yang, Hu, Shaoqin, Wu, Xuanang, Xie, Zhenli, Wang, Yuan, Wang, Bianbian, Li, Xiaopeng, Pei, Yingmei, Gu, Yuhao, Huang, Kai, Huo, Jingxiao, Wei, Anqi, Bi, Cheng, Lu, Zhe, Song, Qian, Xu, Huadong, Kang, Xinjiang, Shao, Shuli, Long, Jiangang, Liu, Jiankang, Zhou, Zhuan, Huang, Rong, Chai, Zuying, Wang, Changhe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171800/ https://www.ncbi.nlm.nih.gov/pubmed/35537054 http://dx.doi.org/10.1073/pnas.2111051119 |
Ejemplares similares
-
Molecular Mechanisms for the Coupling of Endocytosis to Exocytosis in Neurons
por: Xie, Zhenli, et al.
Publicado: (2017) -
α-Synuclein: A Multifunctional Player in Exocytosis, Endocytosis, and Vesicle Recycling
por: Huang, Mingzhu, et al.
Publicado: (2019) -
Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson’s disease-like pathology
por: Wang, Changhe, et al.
Publicado: (2018) -
From structure to function: unveiling the structure of the Na(v) channel–toxin complex
por: Zhou, Zhuan, et al.
Publicado: (2019) -
The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis
por: Jarousse, Nadine, et al.
Publicado: (2001)