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Mimetics of ADP-Ribosylated Histidine through Copper(I)-Catalyzed Click Chemistry

[Image: see text] A convergent synthesis provided nearly perfect τ-ADP-ribosylated histidine isosteres (His*-τ-ADPr) via a copper(I)-catalyzed cycloaddition between an azido-ADP-ribosyl analogue and an oligopeptide carrying a propargyl glycine. Both α- and β-configured azido-ADP-ribosyl analogues ha...

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Detalles Bibliográficos
Autores principales:	Minnee, Hugo, Rack, Johannes G. M., van der Marel, Gijsbert A., Overkleeft, Herman S., Codée, Jeroen D. C., Ahel, Ivan, Filippov, Dmitri V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171823/ https://www.ncbi.nlm.nih.gov/pubmed/35587229 http://dx.doi.org/10.1021/acs.orglett.2c01300

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