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Phylogeny-guided microbiome OTU-specific association test (POST)

BACKGROUND: The relationship between host conditions and microbiome profiles, typically characterized by operational taxonomic units (OTUs), contains important information about the microbial role in human health. Traditional association testing frameworks are challenged by the high dimensionality a...

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Detalles Bibliográficos
Autores principales: Huang, Caizhi, Callahan, Benjamin J., Wu, Michael C., Holloway, Shannon T., Brochu, Hayden, Lu, Wenbin, Peng, Xinxia, Tzeng, Jung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9171974/
https://www.ncbi.nlm.nih.gov/pubmed/35668471
http://dx.doi.org/10.1186/s40168-022-01266-3