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TMEM16A as a potential treatment target for head and neck cancer

Transmembrane protein 16A (TMEM16A) forms a plasma membrane-localized Ca(2+)-activated Cl- channel. Its gene has been mapped to an area on chromosome 11q13, which is amplified in head and neck squamous cell carcinoma (HNSCC). In HNSCC, TMEM16A overexpression is associated with not only high tumor gr...

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Detalles Bibliográficos
Autores principales:	Okuyama, Kohei, Yanamoto, Souichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172006/ https://www.ncbi.nlm.nih.gov/pubmed/35668455 http://dx.doi.org/10.1186/s13046-022-02405-2

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