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Corneal Epithelium–Derived Netrin-1 Alleviates Dry Eye Disease via Regulating Dendritic Cell Activation

PURPOSE: To investigate the expression of corneal epithelium–derived netrin-1 (NTN-1) and its immunoregulatory function in dry eye disease (DED) using a DED mouse model. METHODS: We generated DED mouse models with desiccating stress under scopolamine treatment. RNA sequencing was performed to identi...

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Detalles Bibliográficos
Autores principales:	Yu, Chaoqun, Chen, Peng, Xu, Jing, Wei, Susu, Cao, Qilong, Guo, Chuanlong, Wu, Xianggen, Di, Guohu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172049/ https://www.ncbi.nlm.nih.gov/pubmed/35648640 http://dx.doi.org/10.1167/iovs.63.6.1

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