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Linking unfolded protein response to ovarian cancer cell fusion

BACKGROUND: Polyploid giant cancer cells (PGCCs) have been observed in epithelial ovarian tumors. They can resist antimitotic drugs, thus participating in tumor maintenance and recurrence. Although their origin remains unclear, PGCC formation seems to be enhanced by conditions that trigger the unfol...

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Detalles Bibliográficos
Autores principales: Yart, Lucile, Bastida-Ruiz, Daniel, Allard, Mathilde, Dietrich, Pierre-Yves, Petignat, Patrick, Cohen, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172076/
https://www.ncbi.nlm.nih.gov/pubmed/35672715
http://dx.doi.org/10.1186/s12885-022-09648-4