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Quantifying DNA damage on paper sensors via controlled template-independent DNA polymerization

We report on a paper-based sensor capable of performing template-independent DNA synthesis by terminal deoxynucleotidyl transferase (TdT). Importantly, we observed that TdT efficiently incorporates fluorescently labeled dUTP on to 3′-OH ends of DNA strands in a strictly controllable manner on cellul...

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Detalles Bibliográficos
Autores principales: Xue, Wei, Zhang, Qiang, Chang, Yangyang, Brennan, John D., Li, Yingfu, Liu, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172109/
https://www.ncbi.nlm.nih.gov/pubmed/35756503
http://dx.doi.org/10.1039/d1sc04268h

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