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Effect of chronic intermittent hypoxia-induced HIF-1α/ATAD2 expression on lung cancer stemness

BACKGROUND: Obstructive sleep apnea is associated with increased lung cancer incidence and mortality. Cancer stem cells (CSCs) are characterized by their self-renewing ability, which contributes to metastasis, recurrence, and drug resistance. ATPase family AAA domain-containing protein 2 (ATAD2) ind...

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Detalles Bibliográficos
Autores principales: Hao, Shengyu, Li, Fan, Jiang, Pan, Gao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172155/
https://www.ncbi.nlm.nih.gov/pubmed/35672694
http://dx.doi.org/10.1186/s11658-022-00345-5