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Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice

BACKGROUND: Fresh or dried Persimmon leaves (Diospyros kaki Thunb.) exhibit preventive effects on cardiovascular and cerebrovascular diseases. However, their antidepressant effects and underlying mechanisms are unclear. Thus, we investigated mechanisms responsible for Persimmon leaf extract (PLE) ac...

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Detalles Bibliográficos
Autores principales: Yu, Hui, Shao, Shumin, Xu, Junnan, Guo, Haibiao, Zhong, Zhangfeng, Xu, Jiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172164/
https://www.ncbi.nlm.nih.gov/pubmed/35668445
http://dx.doi.org/10.1186/s13020-022-00609-4

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