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Conformational ensemble of the full-length SARS-CoV-2 nucleocapsid (N) protein based on molecular simulations and SAXS data

The nucleocapsid protein of the SARS-CoV-2 virus comprises two RNA-binding domains and three regions that are intrinsically disordered. While the structures of the RNA-binding domains have been solved using protein crystallography and NMR, current knowledge of the conformations of the full-length nu...

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Detalles Bibliográficos
Autores principales: Różycki, Bartosz, Boura, Evzen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172258/
https://www.ncbi.nlm.nih.gov/pubmed/35696898
http://dx.doi.org/10.1016/j.bpc.2022.106843

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