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Novel derivatives of eugenol as potent anti-inflammatory agents via PPARγ agonism: rational design, synthesis, analysis, PPARγ protein binding assay and computational studies
Eugenol is a natural product abundantly found in clove buds known for its pharmacological activities such as anti-inflammatory, antidiabetic, antioxidant, and anticancer activities. It is well known from the literature that peroxisome proliferator-activated receptors (PPARγ) have been reported to re...
Autores principales: | Anjum, Noor Fathima, Shanmugarajan, Dhivya, Shivaraju, Vasanth Kumar, Faizan, Syed, Naishima, Namburu Lalitha, Prashantha Kumar, B. R., Javid, Saleem, Purohit, Madhusudan N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172550/ https://www.ncbi.nlm.nih.gov/pubmed/35754905 http://dx.doi.org/10.1039/d2ra02116a |
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