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Novel derivatives of eugenol as potent anti-inflammatory agents via PPARγ agonism: rational design, synthesis, analysis, PPARγ protein binding assay and computational studies

Eugenol is a natural product abundantly found in clove buds known for its pharmacological activities such as anti-inflammatory, antidiabetic, antioxidant, and anticancer activities. It is well known from the literature that peroxisome proliferator-activated receptors (PPARγ) have been reported to re...

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Detalles Bibliográficos
Autores principales: Anjum, Noor Fathima, Shanmugarajan, Dhivya, Shivaraju, Vasanth Kumar, Faizan, Syed, Naishima, Namburu Lalitha, Prashantha Kumar, B. R., Javid, Saleem, Purohit, Madhusudan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172550/
https://www.ncbi.nlm.nih.gov/pubmed/35754905
http://dx.doi.org/10.1039/d2ra02116a

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