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DoE-derived continuous and robust process for manufacturing of pharmaceutical-grade wide-range LNPs for RNA-vaccine/drug delivery

Lipid nanoparticle (LNP) technology has become extremely demanding for delivering RNA-products and other drugs. However, there is no platform to manufacture pharmaceutical-grade LNPs with desired particle size from a wide range in continuous mode. We have developed a unique platform to obtain any sp...

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Detalles Bibliográficos
Autores principales: Nag, Kakon, Sarker, Md. Enamul Haq, Kumar, Samir, Khan, Habiba, Chakraborty, Sourav, Islam, Md. Jikrul, Baray, Juwel Chandra, Khan, Maksudur Rahman, Mahmud, Asif, Barman, Uttam, Bhuiya, Eleus Hussain, Mohiuddin, Mohammad, Sultana, Naznin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9172984/
https://www.ncbi.nlm.nih.gov/pubmed/35672337
http://dx.doi.org/10.1038/s41598-022-12100-z

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