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The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies

Magnetic resonance imaging (MRI) has a key role to play at multiple steps of the radiotherapy (RT) treatment planning and delivery process. Development of high-precision RT techniques such as intensity-modulated RT, stereotactic ablative RT, and particle beam therapy has enabled oncologists to escal...

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Autores principales: Srinivasan, Shashank, Dasgupta, Archya, Chatterjee, Abhishek, Baheti, Akshay, Engineer, Reena, Gupta, Tejpal, Murthy, Vedang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173575/
https://www.ncbi.nlm.nih.gov/pubmed/35609219
http://dx.doi.org/10.1200/GO.21.00366
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author Srinivasan, Shashank
Dasgupta, Archya
Chatterjee, Abhishek
Baheti, Akshay
Engineer, Reena
Gupta, Tejpal
Murthy, Vedang
author_facet Srinivasan, Shashank
Dasgupta, Archya
Chatterjee, Abhishek
Baheti, Akshay
Engineer, Reena
Gupta, Tejpal
Murthy, Vedang
author_sort Srinivasan, Shashank
collection PubMed
description Magnetic resonance imaging (MRI) has a key role to play at multiple steps of the radiotherapy (RT) treatment planning and delivery process. Development of high-precision RT techniques such as intensity-modulated RT, stereotactic ablative RT, and particle beam therapy has enabled oncologists to escalate RT dose to the target while restricting doses to organs at risk (OAR). MRI plays a critical role in target volume delineation in various disease sites, thus ensuring that these high-precision techniques can be safely implemented. Accurate identification of gross disease has also enabled selective dose escalation as a means to widen the therapeutic index. Morphological and functional MRI sequences have also facilitated an understanding of temporal changes in target volumes and OAR during a course of RT, allowing for midtreatment volumetric and biological adaptation. The latest advancement in linear accelerator technology has led to the incorporation of an MRI scanner in the treatment unit. MRI-guided RT provides the opportunity for MRI-only workflow along with online adaptation for either target or OAR or both. MRI plays a key role in post-treatment response evaluation and is an important tool for guiding decision making. In this review, we briefly discuss the RT-related applications of MRI in the management of brain, prostate, and GI malignancies.
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spelling pubmed-91735752022-06-08 The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies Srinivasan, Shashank Dasgupta, Archya Chatterjee, Abhishek Baheti, Akshay Engineer, Reena Gupta, Tejpal Murthy, Vedang JCO Glob Oncol REVIEW ARTICLES Magnetic resonance imaging (MRI) has a key role to play at multiple steps of the radiotherapy (RT) treatment planning and delivery process. Development of high-precision RT techniques such as intensity-modulated RT, stereotactic ablative RT, and particle beam therapy has enabled oncologists to escalate RT dose to the target while restricting doses to organs at risk (OAR). MRI plays a critical role in target volume delineation in various disease sites, thus ensuring that these high-precision techniques can be safely implemented. Accurate identification of gross disease has also enabled selective dose escalation as a means to widen the therapeutic index. Morphological and functional MRI sequences have also facilitated an understanding of temporal changes in target volumes and OAR during a course of RT, allowing for midtreatment volumetric and biological adaptation. The latest advancement in linear accelerator technology has led to the incorporation of an MRI scanner in the treatment unit. MRI-guided RT provides the opportunity for MRI-only workflow along with online adaptation for either target or OAR or both. MRI plays a key role in post-treatment response evaluation and is an important tool for guiding decision making. In this review, we briefly discuss the RT-related applications of MRI in the management of brain, prostate, and GI malignancies. Wolters Kluwer Health 2022-05-24 /pmc/articles/PMC9173575/ /pubmed/35609219 http://dx.doi.org/10.1200/GO.21.00366 Text en © 2022 by American Society of Clinical Oncology https://creativecommons.org/licenses/by/4.0/Licensed under the Creative Commons Attribution 4.0 License: http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/)
spellingShingle REVIEW ARTICLES
Srinivasan, Shashank
Dasgupta, Archya
Chatterjee, Abhishek
Baheti, Akshay
Engineer, Reena
Gupta, Tejpal
Murthy, Vedang
The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies
title The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies
title_full The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies
title_fullStr The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies
title_full_unstemmed The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies
title_short The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies
title_sort promise of magnetic resonance imaging in radiation oncology practice in the management of brain, prostate, and gi malignancies
topic REVIEW ARTICLES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173575/
https://www.ncbi.nlm.nih.gov/pubmed/35609219
http://dx.doi.org/10.1200/GO.21.00366
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