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Increased airway resistance can be related to the decrease in the functional capacity in obese women
BACKGROUND AND OBJECTIVE: Obesity can increase the airways resistance, mainly in the periphery, leading to dyspnea perception that can impair the functional capacity. This study aimed to analyze if airways resistance could be related to the walking capacity of women with morbid obesity. METHODS: Thi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173605/ https://www.ncbi.nlm.nih.gov/pubmed/35671283 http://dx.doi.org/10.1371/journal.pone.0267546 |
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author | Perossi, Larissa Holtz, Mayara dos Santos, Daniele Oliveira Perossi, Jéssica de Souza, Hugo Celso Dutra Salgado Junior, Wilson Gastaldi, Ada Clarice |
author_facet | Perossi, Larissa Holtz, Mayara dos Santos, Daniele Oliveira Perossi, Jéssica de Souza, Hugo Celso Dutra Salgado Junior, Wilson Gastaldi, Ada Clarice |
author_sort | Perossi, Larissa |
collection | PubMed |
description | BACKGROUND AND OBJECTIVE: Obesity can increase the airways resistance, mainly in the periphery, leading to dyspnea perception that can impair the functional capacity. This study aimed to analyze if airways resistance could be related to the walking capacity of women with morbid obesity. METHODS: Thirty-seven women with grade III obesity in preoperative bariatric surgery were evaluated using the spirometry test, impulse oscillometry system (IOS), and six-minute walk test (6MWT). Additionally, data about their daily dyspnea perception and physical activity level were collected. RESULTS: Variables of the spirometry test did not detect ventilator disorders. Compared to the predicted values, the IOS identified significant increase in airways resistance (kPa/L/s) (R5: 0.36 (0.34; 0.36) and 0.53 (0.47; 0.61); R20: 0.30 (0.28; 0.30) and 0.41 (0.35; 0.45); R5-20: 0.06 (0.06; 0.06) and 0.14 (0.10; 0.15); X5: -0.03 (-0.04; -0.01) and -0.20 (-0.27; -0.18), respectively). The distance walked in the 6MWT, 491.4±60.4m was significantly correlated to R5 (rho = -0.41, p = 0.01), R5-20 (rho = -0.52, p = 0.001), and X5 (rho = 0.54, p = 0.0006). CONCLUSION: The IOS is able to identify changes in airway resistance even before the onset of symptoms. When evaluated by IOS women with severe obesity and normal spirometry exhibited central and peripheral airways obstruction. The correlations between the IOS and six-minute walk distance suggest that increased peripheral airways resistance could be related to worsening functional capacity. |
format | Online Article Text |
id | pubmed-9173605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-91736052022-06-08 Increased airway resistance can be related to the decrease in the functional capacity in obese women Perossi, Larissa Holtz, Mayara dos Santos, Daniele Oliveira Perossi, Jéssica de Souza, Hugo Celso Dutra Salgado Junior, Wilson Gastaldi, Ada Clarice PLoS One Research Article BACKGROUND AND OBJECTIVE: Obesity can increase the airways resistance, mainly in the periphery, leading to dyspnea perception that can impair the functional capacity. This study aimed to analyze if airways resistance could be related to the walking capacity of women with morbid obesity. METHODS: Thirty-seven women with grade III obesity in preoperative bariatric surgery were evaluated using the spirometry test, impulse oscillometry system (IOS), and six-minute walk test (6MWT). Additionally, data about their daily dyspnea perception and physical activity level were collected. RESULTS: Variables of the spirometry test did not detect ventilator disorders. Compared to the predicted values, the IOS identified significant increase in airways resistance (kPa/L/s) (R5: 0.36 (0.34; 0.36) and 0.53 (0.47; 0.61); R20: 0.30 (0.28; 0.30) and 0.41 (0.35; 0.45); R5-20: 0.06 (0.06; 0.06) and 0.14 (0.10; 0.15); X5: -0.03 (-0.04; -0.01) and -0.20 (-0.27; -0.18), respectively). The distance walked in the 6MWT, 491.4±60.4m was significantly correlated to R5 (rho = -0.41, p = 0.01), R5-20 (rho = -0.52, p = 0.001), and X5 (rho = 0.54, p = 0.0006). CONCLUSION: The IOS is able to identify changes in airway resistance even before the onset of symptoms. When evaluated by IOS women with severe obesity and normal spirometry exhibited central and peripheral airways obstruction. The correlations between the IOS and six-minute walk distance suggest that increased peripheral airways resistance could be related to worsening functional capacity. Public Library of Science 2022-06-07 /pmc/articles/PMC9173605/ /pubmed/35671283 http://dx.doi.org/10.1371/journal.pone.0267546 Text en © 2022 Perossi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Perossi, Larissa Holtz, Mayara dos Santos, Daniele Oliveira Perossi, Jéssica de Souza, Hugo Celso Dutra Salgado Junior, Wilson Gastaldi, Ada Clarice Increased airway resistance can be related to the decrease in the functional capacity in obese women |
title | Increased airway resistance can be related to the decrease in the functional capacity in obese women |
title_full | Increased airway resistance can be related to the decrease in the functional capacity in obese women |
title_fullStr | Increased airway resistance can be related to the decrease in the functional capacity in obese women |
title_full_unstemmed | Increased airway resistance can be related to the decrease in the functional capacity in obese women |
title_short | Increased airway resistance can be related to the decrease in the functional capacity in obese women |
title_sort | increased airway resistance can be related to the decrease in the functional capacity in obese women |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173605/ https://www.ncbi.nlm.nih.gov/pubmed/35671283 http://dx.doi.org/10.1371/journal.pone.0267546 |
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