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High-affinity anti-Arc nanobodies provide tools for structural and functional studies

Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral origin with a vital role in the regulation of synaptic plasticity and memory formation in mammals. However, the mechanistic and structural basis of Arc function is poorly understood. Arc has an N-terminal...

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Detalles Bibliográficos
Autores principales:	Markússon, Sigurbjörn, Hallin, Erik I., Bustad, Helene J., Raasakka, Arne, Xu, Ju, Muruganandam, Gopinath, Loris, Remy, Martinez, Aurora, Bramham, Clive R., Kursula, Petri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173642/ https://www.ncbi.nlm.nih.gov/pubmed/35671319 http://dx.doi.org/10.1371/journal.pone.0269281

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