Biophysical Characterization of the Oligomeric States of Recombinant Immunoglobulins Type-M and Their C1q-Binding Kinetics by Biolayer Interferometry

Immunoglobulins type-M (IgMs) are one of the first antibody classes mobilized during immune responses against pathogens and tumor cells. Binding to specific target antigens enables the interaction with the C1 complex which strongly activates the classical complement pathway. This biological function...

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Detalles Bibliográficos
Autores principales: Chouquet, Anne, Pinto, Andrea J., Hennicke, Julia, Ling, Wai Li, Bally, Isabelle, Schwaigerlehner, Linda, Thielens, Nicole M., Kunert, Renate, Reiser, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173649/
https://www.ncbi.nlm.nih.gov/pubmed/35685087
http://dx.doi.org/10.3389/fbioe.2022.816275

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