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Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in adolescent rats

Development of self-regulatory competencies during adolescence is partially dependent on normative brain maturation. Here, we report that adolescent rats as compared to adults exhibit impulsive and compulsive-like behavioral traits, the latter being associated with lower expression of mRNA levels of...

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Detalles Bibliográficos
Autores principales: Jadhav, Kshitij S., Bernheim, Aurélien P., Aeschlimann, Léa, Kirschmann, Guylène, Decosterd, Isabelle, Hoffman, Alexander F., Lupica, Carl R., Boutrel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173752/
https://www.ncbi.nlm.nih.gov/pubmed/35584117
http://dx.doi.org/10.1073/pnas.2121247119