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Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface

Influenza virus hemagglutinin (HA) has been the primary target for influenza vaccine development. Broadly protective antibodies targeting conserved regions of the HA unlock the possibility of generating universal influenza immunity. Two group 2 influenza A chimeric HAs, cH4/3 and cH15/3, were previo...

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Detalles Bibliográficos
Autores principales:	Zhu, Xueyong, Han, Julianna, Sun, Weina, Puente-Massaguer, Eduard, Yu, Wenli, Palese, Peter, Krammer, Florian, Ward, Andrew B., Wilson, Ian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173763/ https://www.ncbi.nlm.nih.gov/pubmed/35594401 http://dx.doi.org/10.1073/pnas.2200821119

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