Serodolin, a β-arrestin–biased ligand of 5-HT(7) receptor, attenuates pain-related behaviors

G protein–coupled receptors (GPCRs) are involved in regulation of manifold physiological processes through coupling to heterotrimeric G proteins upon ligand stimulation. Classical therapeutically active drugs simultaneously initiate several downstream signaling pathways, whereas biased ligands, whic...

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Detalles Bibliográficos
Autores principales: El Khamlichi, Chayma, Reverchon, Flora, Hervouet-Coste, Nadège, Robin, Elodie, Chopin, Nicolas, Deau, Emmanuel, Madouri, Fahima, Guimpied, Cyril, Colas, Cyril, Menuet, Arnaud, Inoue, Asuka, Bojarski, Andrzej J., Guillaumet, Gérald, Suzenet, Franck, Reiter, Eric, Morisset-Lopez, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173812/
https://www.ncbi.nlm.nih.gov/pubmed/35594393
http://dx.doi.org/10.1073/pnas.2118847119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173812/
https://www.ncbi.nlm.nih.gov/pubmed/35594393
http://dx.doi.org/10.1073/pnas.2118847119

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