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Serodolin, a β-arrestin–biased ligand of 5-HT(7) receptor, attenuates pain-related behaviors

G protein–coupled receptors (GPCRs) are involved in regulation of manifold physiological processes through coupling to heterotrimeric G proteins upon ligand stimulation. Classical therapeutically active drugs simultaneously initiate several downstream signaling pathways, whereas biased ligands, whic...

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Detalles Bibliográficos
Autores principales:	El Khamlichi, Chayma, Reverchon, Flora, Hervouet-Coste, Nadège, Robin, Elodie, Chopin, Nicolas, Deau, Emmanuel, Madouri, Fahima, Guimpied, Cyril, Colas, Cyril, Menuet, Arnaud, Inoue, Asuka, Bojarski, Andrzej J., Guillaumet, Gérald, Suzenet, Franck, Reiter, Eric, Morisset-Lopez, Séverine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173812/ https://www.ncbi.nlm.nih.gov/pubmed/35594393 http://dx.doi.org/10.1073/pnas.2118847119

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