Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) constitutes 10–20% of breast cancers and is challenging to treat due to a lack of effective targeted therapies. Previous studies in TNBC cell lines showed in vitro growth inhibition when JQ1 or GSK2801 were administered alone, and enhanced activity wh...

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Detalles Bibliográficos
Autores principales: Yellapu, Nanda Kumar, Ly, Thuc, Sardiu, Mihaela E., Pei, Dong, Welch, Danny R., Thompson, Jeffery A., Koestler, Devin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9173973/
https://www.ncbi.nlm.nih.gov/pubmed/35672711
http://dx.doi.org/10.1186/s12885-022-09690-2

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