Structural basis for MTA1c-mediated DNA N6-adenine methylation

DNA N6-adenine methylation (6 mA) has recently been found to play a crucial role in epigenetic regulation in eukaryotes. MTA1c, a newly discovered 6 mA methyltransferase complex in ciliates, is composed of MTA1, MTA9, p1 and p2 subunits and specifically methylates ApT dinucleotides, yet its mechanis...

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Detalles Bibliográficos
Autores principales: Chen, Jiyun, Hu, Rong, Chen, Ying, Lin, Xiaofeng, Xiang, Wenwen, Chen, Hong, Yao, Canglin, Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174199/
https://www.ncbi.nlm.nih.gov/pubmed/35672411
http://dx.doi.org/10.1038/s41467-022-31060-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174199/
https://www.ncbi.nlm.nih.gov/pubmed/35672411
http://dx.doi.org/10.1038/s41467-022-31060-6

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