pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils

Self-assembly and fibril formation play important roles in protein behaviour. Amyloid fibril formation is well-studied due to its role in neurodegenerative diseases and characterized by refolding of the protein into predominantly β-sheet form. However, much less is known about the assembly of protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Pohl, Christin, Effantin, Gregory, Kandiah, Eaazhisai, Meier, Sebastian, Zeng, Guanghong, Streicher, Werner, Segura, Dorotea Raventos, Mygind, Per H., Sandvang, Dorthe, Nielsen, Line Anker, Peters, Günther H. J., Schoehn, Guy, Mueller-Dieckmann, Christoph, Noergaard, Allan, Harris, Pernille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174238/
https://www.ncbi.nlm.nih.gov/pubmed/35672293
http://dx.doi.org/10.1038/s41467-022-30462-w

Ejemplares similares

Ejemplares similares