Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure

The host’s gene expression and gene regulatory response to pathogen exposure can be influenced by a combination of the host’s genetic background, the type of and exposure time to pathogens. Here we provide a detailed dissection of this using single-cell RNA-sequencing of 1.3M peripheral blood mononu...

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Detalles Bibliográficos
Autores principales: Oelen, Roy, de Vries, Dylan H., Brugge, Harm, Gordon, M. Grace, Vochteloo, Martijn, Ye, Chun J., Westra, Harm-Jan, Franke, Lude, van der Wijst, Monique G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174272/
https://www.ncbi.nlm.nih.gov/pubmed/35672358
http://dx.doi.org/10.1038/s41467-022-30893-5

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