Cargando…

5-Azacytidine increases tanshinone production in Salvia miltiorrhiza hairy roots through epigenetic modulation

Recent studies have indicated strong connections between epigenetic modulation and secondary metabolites in plants. It is vital to understand the roles of epigenetics in the production of secondary metabolites. In this study, the inhibitor of DNA methylation 5-azacytidine (5-Az) was used on the hair...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Bo-Cheng, Lee, Meng-Shiou, Lin, Ming-Kuem, Chang, Wen-Te
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174287/ https://www.ncbi.nlm.nih.gov/pubmed/35672334 http://dx.doi.org/10.1038/s41598-022-12577-8

Ejemplares similares

Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering
por: Wei, Tao, et al.
Publicado: (2019)

Proteomic analysis reveals novel insights into tanshinones biosynthesis in Salvia miltiorrhiza hairy roots
por: Contreras, Angela, et al.
Publicado: (2019)

One-Step Regeneration of Hairy Roots to Induce High Tanshinone Plants in Salvia miltiorrhiza
por: Su, Yuekai, et al.
Publicado: (2022)

Tanshinone and salvianolic acid biosynthesis are regulated by SmMYB98 in Salvia miltiorrhiza hairy roots
por: Hao, Xiaolong, et al.
Publicado: (2020)

Overexpression of SmSCR1 Promotes Tanshinone Accumulation and Hairy Root Growth in Salvia miltiorrhiza
por: Zhou, Wei, et al.
Publicado: (2022)

Diterpenoid Tanshinones and Phenolic Acids from Cultured Hairy Roots of Salvia miltiorrhiza Bunge and Their Antimicrobial Activities
por: Zhao, Jianglin, et al.
Publicado: (2011)

Different Roles of the Mevalonate and Methylerythritol Phosphate Pathways in Cell Growth and Tanshinone Production of Salvia miltiorrhiza Hairy Roots
por: Yang, Dongfeng, et al.
Publicado: (2012)

Ag(+) as a More Effective Elicitor for Production of Tanshinones than Phenolic Acids in Salvia miltiorrhiza Hairy Roots
por: Xing, Bingcong, et al.
Publicado: (2014)

Molecular cloning and characterization of five SmGRAS genes associated with tanshinone biosynthesis in Salvia miltiorrhiza hairy roots
por: Bai, Zhenqing, et al.
Publicado: (2017)

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures
por: Cheng, Qiqing, et al.
Publicado: (2013)

Lipopolysaccharide Enhances Tanshinone Biosynthesis via a Ca(2+)-Dependent Manner in Salvia miltiorrhiza Hairy Roots
por: Zhang, Bin, et al.
Publicado: (2020)

Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots
por: Du, Xuhong, et al.
Publicado: (2015)

Methyl jasmonate induction of tanshinone biosynthesis in Salvia miltiorrhiza hairy roots is mediated by JASMONATE ZIM-DOMAIN repressor proteins
por: Shi, Min, et al.
Publicado: (2016)

Antihypertension Induced by Tanshinone IIA Isolated from the Roots of Salvia miltiorrhiza
por: Chan, Paul, et al.
Publicado: (2011)

Spatiotemporal and Transcriptional Characterization on Tanshinone Initial Synthesis in Salvia miltiorrhiza Roots
por: Lin, Caicai, et al.
Publicado: (2022)

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza
por: Jiang, Zhouqian, et al.
Publicado: (2019)

The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in salvia miltiorrhiza hairy roots
por: Li, Qi, et al.
Publicado: (2022)

The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza
por: Ma, Xiao-Hui, et al.
Publicado: (2015)

Salvia castanea Hairy Roots are More Tolerant to Phosphate Deficiency than Salvia miltiorrhiza Hairy Roots Based on the Secondary Metabolism and Antioxidant Defenses
por: Liu, Lin, et al.
Publicado: (2018)

Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish
por: Wei, Yingjie, et al.
Publicado: (2012)

Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza
por: Gao, Wei, et al.
Publicado: (2014)

The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production in Salvia miltiorrhiza
por: Xu, Zhichao, et al.
Publicado: (2017)

Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions
por: Adams, James David, et al.
Publicado: (2006)

Activation tagging in Salvia miltiorrhiza can cause increased leaf size and accumulation of tanshinone I and IIA in its roots
por: Ho, Hsin-Shueh, et al.
Publicado: (2013)

Transcriptomic analysis reveals the GRAS family genes respond to gibberellin in Salvia miltiorrhiza hairy roots
por: Li, Wenrui, et al.
Publicado: (2020)

Extracellular ATP-induced NO production and its dependence on membrane Ca(2+) flux in Salvia miltiorrhiza hairy roots
por: Wu, Shu-Jing, et al.
Publicado: (2008)

Effects of Abscisic Acid, Gibberellin, Ethylene and Their Interactions on Production of Phenolic Acids in Salvia miltiorrhiza Bunge Hairy Roots
por: Liang, Zongsuo, et al.
Publicado: (2013)

Inhibition of bone resorption by Tanshinone VI isolated from Salvia miltiorrhiza Bunge
por: Nicolin, V., et al.
Publicado: (2010)

Transcriptomic analysis reveals potential genes involved in tanshinone biosynthesis in Salvia miltiorrhiza
por: Chang, Yujie, et al.
Publicado: (2019)

Comparative transcriptome analyses of different Salvia miltiorrhiza varieties during the accumulation of tanshinones
por: Zhou, Jingwen, et al.
Publicado: (2021)

An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen)
por: Naz, Irum, et al.
Publicado: (2020)

Characteristics of Salvia miltiorrhiza methylome and the regulatory mechanism of DNA methylation in tanshinone biosynthesis
por: Li, Jiang, et al.
Publicado: (2023)

Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation
por: Gao, Hongwei, et al.
Publicado: (2018)

Integrative transcriptomic and metabolomic analyses unveil tanshinone biosynthesis in Salvia miltiorrhiza root under N starvation stress
por: Lu, Li-Lan, et al.
Publicado: (2022)

SmMYB36, a Novel R2R3-MYB Transcription Factor, Enhances Tanshinone Accumulation and Decreases Phenolic Acid Content in Salvia miltiorrhiza Hairy Roots
por: Ding, Kai, et al.
Publicado: (2017)

Transcriptome Analysis of Medicinal Plant Salvia miltiorrhiza and Identification of Genes Related to Tanshinone Biosynthesis
por: Yang, Lei, et al.
Publicado: (2013)

Transcription Factor SmWRKY1 Positively Promotes the Biosynthesis of Tanshinones in Salvia miltiorrhiza
por: Cao, Wenzhi, et al.
Publicado: (2018)

Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers
por: Xing, Lu, et al.
Publicado: (2017)

The SmNPR4-SmTGA5 module regulates SA-mediated phenolic acid biosynthesis in Salvia miltiorrhiza hairy roots
por: Ding, Meiling, et al.
Publicado: (2023)

UHPLC-HRMS(n) Analysis Reveals the Dynamic Metabonomic Responses of Salvia miltiorrhiza Hairy Roots to Polysaccharide Fraction from Trichoderma atroviride
por: Ming, Qianliang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_k4knr05bnnr2129rgugi6qnjd8