DAT and TH expression marks human Parkinson’s disease in peripheral immune cells

Parkinson’s disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investigational purposes in human patients because midbrain tissue i...

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Detalles Bibliográficos
Autores principales: Gopinath, Adithya, Mackie, Phillip, Hashimi, Basil, Buchanan, Anna Marie, Smith, Aidan R., Bouchard, Rachel, Shaw, Gerry, Badov, Martin, Saadatpour, Leila, Gittis, Aryn, Ramirez-Zamora, Adolfo, Okun, Michael S., Streit, Wolfgang J., Hashemi, Parastoo, Khoshbouei, Habibeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174333/
https://www.ncbi.nlm.nih.gov/pubmed/35672374
http://dx.doi.org/10.1038/s41531-022-00333-8

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