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Negative Regulator Nlrc3-like Maintain the Balanced Innate Immune Response During Mycobacterial Infection in Zebrafish

The NOD-like receptors (NLRs) have been shown to be involved in infection and autoinflammatory disease. Previously, we identified a zebrafish NLR, nlrc3-like, required for macrophage homeostasis in the brain under physiological conditions. Here, we found that a deficiency of nlrc3-like leads to decr...

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Detalles Bibliográficos
Autores principales: Niu, Liangfei, Luo, Geyang, Liang, Rui, Qiu, Chenli, Yang, Jianwei, Xie, Lingling, Zhang, Kaile, Tian, Yu, Wang, Decheng, Song, Shu, Takiff, Howard E., Wong, Ka-Wing, Fan, Xiaoyong, Gao, Qian, Yan, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174460/
https://www.ncbi.nlm.nih.gov/pubmed/35693809
http://dx.doi.org/10.3389/fimmu.2022.893611