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Mafa-dependent GABAergic activity promotes mouse neonatal apneas

While apneas are associated with multiple pathological and fatal conditions, the underlying molecular mechanisms remain elusive. We report that a mutated form of the transcription factor Mafa (Mafa(4A)) that prevents phosphorylation of the Mafa protein leads to an abnormally high incidence of breath...

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Detalles Bibliográficos
Autores principales: Lecoin, Laure, Dempsey, Bowen, Garancher, Alexandra, Bourane, Steeve, Ruffault, Pierre-Louis, Morin-Surun, Marie-Pierre, Rocques, Nathalie, Goulding, Martyn, Eychène, Alain, Pouponnot, Celio, Fortin, Gilles, Champagnat, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174494/
https://www.ncbi.nlm.nih.gov/pubmed/35672398
http://dx.doi.org/10.1038/s41467-022-30825-3