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Mafa-dependent GABAergic activity promotes mouse neonatal apneas
While apneas are associated with multiple pathological and fatal conditions, the underlying molecular mechanisms remain elusive. We report that a mutated form of the transcription factor Mafa (Mafa(4A)) that prevents phosphorylation of the Mafa protein leads to an abnormally high incidence of breath...
Autores principales: | Lecoin, Laure, Dempsey, Bowen, Garancher, Alexandra, Bourane, Steeve, Ruffault, Pierre-Louis, Morin-Surun, Marie-Pierre, Rocques, Nathalie, Goulding, Martyn, Eychène, Alain, Pouponnot, Celio, Fortin, Gilles, Champagnat, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174494/ https://www.ncbi.nlm.nih.gov/pubmed/35672398 http://dx.doi.org/10.1038/s41467-022-30825-3 |
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