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Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes
The bromodomain and extra-terminal domain proteins (BETs) family serve as epigenetic “readers”, which recognize the acetylated histones and recruit transcriptional regulator complexes to chromatin, eventually regulating gene transcription. Accumulating evidences demonstrate that pan BET inhibitors (...
Autores principales: | Lin, Zhirong, Li, Zhenzhen, Guo, Zhen, Cao, Yanjun, Li, Jingyan, Liu, Peiqing, Li, Zhuoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174549/ https://www.ncbi.nlm.nih.gov/pubmed/35694272 http://dx.doi.org/10.3389/fphar.2022.887991 |
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