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Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer

BACKGROUND: Pyruvate dehydrogenase (PDH) complex converts pyruvate into acetyl-CoA by pyruvate decarboxylation, which drives energy metabolism during cell growth, including prostate cancer (PCa) cell growth. The major catalytic subunit of PDH, PDHA1, is regulated by phosphorylation/dephosphorylation...

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Detalles Bibliográficos
Autores principales:	Nunes-Xavier, Caroline E., Mingo, Janire, Emaldi, Maite, Flem-Karlsen, Karine, Mælandsmo, Gunhild M., Fodstad, Øystein, Llarena, Roberto, López, José I., Pulido, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174590/ https://www.ncbi.nlm.nih.gov/pubmed/35692804 http://dx.doi.org/10.3389/fonc.2022.873516

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