Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway

Background and aims: Saikosaponin d (SSd) has a steroidal structure and significant anti-inflammatory effects. The purpose of this study was to explore the mechanism underlying SSd’s inhibitory effects on liver fibrosis. Methods: Wild-type and estrogen receptor knockout (ERKO) mice were treated with...

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Detalles Bibliográficos
Autores principales: Zhang, Kehui, Lin, Liubing, Zhu, Yingying, Zhang, Na, Zhou, Meng’en, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174603/
https://www.ncbi.nlm.nih.gov/pubmed/35694250
http://dx.doi.org/10.3389/fphar.2022.894981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174603/
https://www.ncbi.nlm.nih.gov/pubmed/35694250
http://dx.doi.org/10.3389/fphar.2022.894981

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