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The Phosphodiesterase Inhibitor Tadalafil Promotes Splenic Retention of Plasmodium falciparum Gametocytes in Humanized Mice

The persistence of erythrocytes infected with Plasmodium falciparum gametocytes in the bloodstream is closely related to the modulation of their mechanical properties. New drugs that increase the stiffness of infected erythrocytes may thus represent a novel approach to block malaria parasite transmi...

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Detalles Bibliográficos
Autores principales: Barbieri, Daniela, Gomez, Lina, Royer, Ludivine, Dupuy, Florian, Franetich, Jean-François, Tefit, Maurel, N’Dri, Marie-Esther, Mazier, Dominique, Silvie, Olivier, Moreno-Sabater, Alicia, Lavazec, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174641/
https://www.ncbi.nlm.nih.gov/pubmed/35694548
http://dx.doi.org/10.3389/fcimb.2022.883759