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Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST

BACKGROUND: The disparities of hr-HPV infection among races/ethnicities have not been fully discussed. This study aimed to investigate the difference of hr-HPV infection between Chinese Han and Mongols minority women in Inner Mongolia. METHODS: Genotyping and histopathology data of Chinese Han and M...

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Autores principales: Guo, Chunlei, Du, Hui, Qu, Xinfeng, Duan, Xianzhi, Li, Jingran, Li, Ruizhen, Jin, Hua, Wang, Chun, Zhao, Chao, Bao, Juncui, Luo, Hongxue, Wei, Lihui, Belinson, J. L., Wu, Ruifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174663/
https://www.ncbi.nlm.nih.gov/pubmed/35692337
http://dx.doi.org/10.3389/fpubh.2022.840879
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author Guo, Chunlei
Du, Hui
Qu, Xinfeng
Duan, Xianzhi
Li, Jingran
Li, Ruizhen
Jin, Hua
Wang, Chun
Zhao, Chao
Bao, Juncui
Luo, Hongxue
Wei, Lihui
Belinson, J. L.
Wu, Ruifang
author_facet Guo, Chunlei
Du, Hui
Qu, Xinfeng
Duan, Xianzhi
Li, Jingran
Li, Ruizhen
Jin, Hua
Wang, Chun
Zhao, Chao
Bao, Juncui
Luo, Hongxue
Wei, Lihui
Belinson, J. L.
Wu, Ruifang
author_sort Guo, Chunlei
collection PubMed
description BACKGROUND: The disparities of hr-HPV infection among races/ethnicities have not been fully discussed. This study aimed to investigate the difference of hr-HPV infection between Chinese Han and Mongols minority women in Inner Mongolia. METHODS: Genotyping and histopathology data of Chinese Han and Mongols minority women in Inner Mongolia from Chinese Multi-Center Screening Trial were used to analyze the hr-HPV prevalence, and type-specific distribution in abnormal pathology results. RESULTS: The hr-HPV infection rates of Han women was 15.9% while of Mongols was 21.6% (P < 0.001). The most prevalent genotypes in Han women were ranked as HPV-16,−52,−18/-58,−31/-39, and−59 while in Mongols were−16,−31,−58,−18 and−52. When analyzing the age-specific of hr-HPV infection, two peaks were found at age of 40–44 (20.5%) and 55–59 (23.5%) years in Han women while three peaks were observed at age of 30–34 (22.1%), 45–49 (22.9%), and 55–59 (31.8%) years, respectively, in Mongols. HPV-16 accounting for 62.5 and 53.8% of the CINII+ in Han and Mongols, respectively. CONCLUSION: The prevalence of hr-HPV was significantly different between the Han and Mongols minority women in Inner Mongolia, races/ethnicities background should be taken into consideration for the refinement of cervical cancer screening strategies and vaccine implementation in China.
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spelling pubmed-91746632022-06-09 Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST Guo, Chunlei Du, Hui Qu, Xinfeng Duan, Xianzhi Li, Jingran Li, Ruizhen Jin, Hua Wang, Chun Zhao, Chao Bao, Juncui Luo, Hongxue Wei, Lihui Belinson, J. L. Wu, Ruifang Front Public Health Public Health BACKGROUND: The disparities of hr-HPV infection among races/ethnicities have not been fully discussed. This study aimed to investigate the difference of hr-HPV infection between Chinese Han and Mongols minority women in Inner Mongolia. METHODS: Genotyping and histopathology data of Chinese Han and Mongols minority women in Inner Mongolia from Chinese Multi-Center Screening Trial were used to analyze the hr-HPV prevalence, and type-specific distribution in abnormal pathology results. RESULTS: The hr-HPV infection rates of Han women was 15.9% while of Mongols was 21.6% (P < 0.001). The most prevalent genotypes in Han women were ranked as HPV-16,−52,−18/-58,−31/-39, and−59 while in Mongols were−16,−31,−58,−18 and−52. When analyzing the age-specific of hr-HPV infection, two peaks were found at age of 40–44 (20.5%) and 55–59 (23.5%) years in Han women while three peaks were observed at age of 30–34 (22.1%), 45–49 (22.9%), and 55–59 (31.8%) years, respectively, in Mongols. HPV-16 accounting for 62.5 and 53.8% of the CINII+ in Han and Mongols, respectively. CONCLUSION: The prevalence of hr-HPV was significantly different between the Han and Mongols minority women in Inner Mongolia, races/ethnicities background should be taken into consideration for the refinement of cervical cancer screening strategies and vaccine implementation in China. Frontiers Media S.A. 2022-05-25 /pmc/articles/PMC9174663/ /pubmed/35692337 http://dx.doi.org/10.3389/fpubh.2022.840879 Text en Copyright © 2022 Guo, Du, Qu, Duan, Li, Li, Jin, Wang, Zhao, Bao, Luo, Wei, Belinson and Wu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Guo, Chunlei
Du, Hui
Qu, Xinfeng
Duan, Xianzhi
Li, Jingran
Li, Ruizhen
Jin, Hua
Wang, Chun
Zhao, Chao
Bao, Juncui
Luo, Hongxue
Wei, Lihui
Belinson, J. L.
Wu, Ruifang
Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST
title Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST
title_full Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST
title_fullStr Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST
title_full_unstemmed Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST
title_short Prevalence of Human Papillomavirus Among Chinese Han and Mongols Minority Women in Inner Mongolia, China: Reflected by Self-Collected Samples in CHIMUST
title_sort prevalence of human papillomavirus among chinese han and mongols minority women in inner mongolia, china: reflected by self-collected samples in chimust
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174663/
https://www.ncbi.nlm.nih.gov/pubmed/35692337
http://dx.doi.org/10.3389/fpubh.2022.840879
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