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The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis

Background: Ferroptosis is a novel mechanism of programmed cell death coined in 2012, which has been found to play important roles in human health and disease. In the past decade, ferroptosis research has seen booming growth worldwide. The aim of this study was to visualize the scientific outputs an...

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Detalles Bibliográficos
Autores principales: Li, Guoli, Liang, Yumei, Yang, Hongyu, Zhang, Weiru, Xie, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174675/
https://www.ncbi.nlm.nih.gov/pubmed/35693942
http://dx.doi.org/10.3389/fcell.2022.841724
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author Li, Guoli
Liang, Yumei
Yang, Hongyu
Zhang, Weiru
Xie, Tingting
author_facet Li, Guoli
Liang, Yumei
Yang, Hongyu
Zhang, Weiru
Xie, Tingting
author_sort Li, Guoli
collection PubMed
description Background: Ferroptosis is a novel mechanism of programmed cell death coined in 2012, which has been found to play important roles in human health and disease. In the past decade, ferroptosis research has seen booming growth worldwide. The aim of this study was to visualize the scientific outputs and research trends of ferroptosis in the field of cancer. Methods: The raw data of publications were retrieved from the Web of Science Core Collection on 19 December 2021. The information on the impact factor (IF) and Journal Citation Reports (JCR) division were obtained from the website of Web of Science. Two kinds of software (CiteSpace and VOSviewer) were used to perform visualized analysis. Results: From 2012 to 2021, a total of 1833 publications related to ferroptosis in cancer were identified for final analysis. The annual number of citations and publications grew exponentially over the past decade. China (1,092) and United States (489) had the highest number of publications; Central South University and Guangzhou Medical University were the most productive institutions. Daolin Tang and Scott J Dixon were the most active authors ranked by most productive and co-cited, respectively. The journals with the highest output and co-citation frequency were Biochemical and Biophysical Research Communications and Cell, respectively. Among the 1833 publications, four were identified with citations more than 1000 times. Six co-cited references had a citation burst duration until 2021. Analysis of keywords suggested the current research of ferroptosis in cancer clusters in 9 hotspots and newly emerging frontier may be “multidrug resistance”. Conclusion: Cancer research is the major area of active research in ferroptosis. Our results provide a global landscape of the ferroptosis research in cancer from 2012 to 2021, which serves as a reference for future studies in this field.
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spelling pubmed-91746752022-06-09 The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis Li, Guoli Liang, Yumei Yang, Hongyu Zhang, Weiru Xie, Tingting Front Cell Dev Biol Cell and Developmental Biology Background: Ferroptosis is a novel mechanism of programmed cell death coined in 2012, which has been found to play important roles in human health and disease. In the past decade, ferroptosis research has seen booming growth worldwide. The aim of this study was to visualize the scientific outputs and research trends of ferroptosis in the field of cancer. Methods: The raw data of publications were retrieved from the Web of Science Core Collection on 19 December 2021. The information on the impact factor (IF) and Journal Citation Reports (JCR) division were obtained from the website of Web of Science. Two kinds of software (CiteSpace and VOSviewer) were used to perform visualized analysis. Results: From 2012 to 2021, a total of 1833 publications related to ferroptosis in cancer were identified for final analysis. The annual number of citations and publications grew exponentially over the past decade. China (1,092) and United States (489) had the highest number of publications; Central South University and Guangzhou Medical University were the most productive institutions. Daolin Tang and Scott J Dixon were the most active authors ranked by most productive and co-cited, respectively. The journals with the highest output and co-citation frequency were Biochemical and Biophysical Research Communications and Cell, respectively. Among the 1833 publications, four were identified with citations more than 1000 times. Six co-cited references had a citation burst duration until 2021. Analysis of keywords suggested the current research of ferroptosis in cancer clusters in 9 hotspots and newly emerging frontier may be “multidrug resistance”. Conclusion: Cancer research is the major area of active research in ferroptosis. Our results provide a global landscape of the ferroptosis research in cancer from 2012 to 2021, which serves as a reference for future studies in this field. Frontiers Media S.A. 2022-05-25 /pmc/articles/PMC9174675/ /pubmed/35693942 http://dx.doi.org/10.3389/fcell.2022.841724 Text en Copyright © 2022 Li, Liang, Yang, Zhang and Xie. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Li, Guoli
Liang, Yumei
Yang, Hongyu
Zhang, Weiru
Xie, Tingting
The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis
title The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis
title_full The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis
title_fullStr The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis
title_full_unstemmed The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis
title_short The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis
title_sort research landscape of ferroptosis in cancer: a bibliometric analysis
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174675/
https://www.ncbi.nlm.nih.gov/pubmed/35693942
http://dx.doi.org/10.3389/fcell.2022.841724
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