ADAR1 Prevents R-loop Accumulation-Driven ATR Pathway Activation in Ovarian Cancer

Adenosine (A)-to-inosine (I) RNA editing is the most prevalent RNA editing mechanism, in which adenosine deaminase acting on RNA 1 (ADAR1) is a major adenosine deaminase. Increasing evidence suggests that editing dysregulation of ADAR1 plays an important role in human tumorigenesis, while the underl...

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Detalles Bibliográficos
Autores principales: Cui, Hanwei, Yi, Qian, Tian, Min, Yang, Hai Ting, Liang, Yuteng, Huang, Jie, Zeng, Qi, Sun, Weichao, Han, Jian, Guo, Jianxin, Yu, Zhiying, Liu, Wenlan, Ye, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174845/
https://www.ncbi.nlm.nih.gov/pubmed/35711824
http://dx.doi.org/10.7150/jca.72108

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