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Transcriptome sequencing reveals altered ciliogenesis under hypoxia in nasal epithelial cells from chronic rhinosinusitis with nasal polyps

BACKGROUND: Hypoxia is considered a key factor in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the specific mechanism driving polypogenesis under hypoxic conditions is unclear. This study aimed to explore hypoxia‐induced alterations in the transcriptome of human na...

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Detalles Bibliográficos
Autores principales: Jiao, Jian, Hu, Puqi, Zhuang, Mengyan, Li, Ying, Cai, Chao, Wang, Xiangdong, Zhang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174880/
https://www.ncbi.nlm.nih.gov/pubmed/35702726
http://dx.doi.org/10.1002/clt2.12168