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A preclinical model of peripheral T‐cell lymphoma GATA3 reveals DNA damage response pathway vulnerability

Peripheral T‐cell lymphoma (PTCL) represents a rare group of heterogeneous diseases in urgent need of effective treatments. A scarcity of disease‐relevant preclinical models hinders research advances. Here, we isolated a novel mouse (m)PTCL by serially transplanting a lymphoma from a germinal center...

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Detalles Bibliográficos
Autores principales: Kuczynski, Elizabeth A, Morlino, Giulia, Peter, Alison, Coenen‐Stass, Anna M L, Moss, Jennifer I, Wali, Neha, Delpuech, Oona, Reddy, Avinash, Solanki, Anisha, Sinclair, Charles, Calado, Dinis P, Carnevalli, Larissa S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174882/
https://www.ncbi.nlm.nih.gov/pubmed/35510955
http://dx.doi.org/10.15252/emmm.202215816