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PanaxGDB: A Comprehensive Platform for Panax

The genus Panax is a valuable natural medicinal source used worldwide that contains high levels of triterpenoid saponins with extensive pharmacological activities. In past decades, molecular biotechnology and breeding techniques have been respectively used to generate omics data and information on c...

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Autores principales: Lin, Yuan, Hao, Bing, Lu, Ying Chun, Dong, Yang, Li, Ying, Zhang, Guang Hui, Yang, Zi Jiang, Xiang, Gui Sheng, Liu, Guan Ze, Li, Xue Jiao, Zhu, Qin, Yang, Qing Hui, Li, Xu Zhen, Yang, Sheng Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174995/
https://www.ncbi.nlm.nih.gov/pubmed/35693187
http://dx.doi.org/10.3389/fpls.2022.883818
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author Lin, Yuan
Hao, Bing
Lu, Ying Chun
Dong, Yang
Li, Ying
Zhang, Guang Hui
Yang, Zi Jiang
Xiang, Gui Sheng
Liu, Guan Ze
Li, Xue Jiao
Zhu, Qin
Yang, Qing Hui
Li, Xu Zhen
Yang, Sheng Chao
author_facet Lin, Yuan
Hao, Bing
Lu, Ying Chun
Dong, Yang
Li, Ying
Zhang, Guang Hui
Yang, Zi Jiang
Xiang, Gui Sheng
Liu, Guan Ze
Li, Xue Jiao
Zhu, Qin
Yang, Qing Hui
Li, Xu Zhen
Yang, Sheng Chao
author_sort Lin, Yuan
collection PubMed
description The genus Panax is a valuable natural medicinal source used worldwide that contains high levels of triterpenoid saponins with extensive pharmacological activities. In past decades, molecular biotechnology and breeding techniques have been respectively used to generate omics data and information on cultivars primarily from Panax ginseng (ginseng), Panax quinquefolium (American ginseng), and Panax notoginseng (Sanqi) to biosynthesize valuable saponins, improve product quality, and conduct cost-controlled cultivation. Although much data have been produced, there are concerns that redundant data might be generated and that relatively scattered data might be overlooked. Therefore, many scientists desire a reliable, comprehensive omics database of the Panax genus that could save time and promote integrated analysis. Therefore, to provide all-inclusive, reliable, and valuable information on the Panax genus, PanaxGDB, an open comprehensive database that integrates data on omics and information on varieties, was established. The database contains information on nearly 600 compounds from 12 Panax species, draft genomic sequences with annotations and gene expression levels, single nucleotide polymorphisms, genome-wide association analysis based on agronomic traits, globally collected germplasm information, summaries, omics data of the Panax genus, and online versatile analytic tools. The Panax genus database will be updated when new data are released to continue serving as a central portal to boost research on the biology and functions of Panax. PanaxGDB is available at: http://panaxGDB.ynau.edu.cn.
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spelling pubmed-91749952022-06-09 PanaxGDB: A Comprehensive Platform for Panax Lin, Yuan Hao, Bing Lu, Ying Chun Dong, Yang Li, Ying Zhang, Guang Hui Yang, Zi Jiang Xiang, Gui Sheng Liu, Guan Ze Li, Xue Jiao Zhu, Qin Yang, Qing Hui Li, Xu Zhen Yang, Sheng Chao Front Plant Sci Plant Science The genus Panax is a valuable natural medicinal source used worldwide that contains high levels of triterpenoid saponins with extensive pharmacological activities. In past decades, molecular biotechnology and breeding techniques have been respectively used to generate omics data and information on cultivars primarily from Panax ginseng (ginseng), Panax quinquefolium (American ginseng), and Panax notoginseng (Sanqi) to biosynthesize valuable saponins, improve product quality, and conduct cost-controlled cultivation. Although much data have been produced, there are concerns that redundant data might be generated and that relatively scattered data might be overlooked. Therefore, many scientists desire a reliable, comprehensive omics database of the Panax genus that could save time and promote integrated analysis. Therefore, to provide all-inclusive, reliable, and valuable information on the Panax genus, PanaxGDB, an open comprehensive database that integrates data on omics and information on varieties, was established. The database contains information on nearly 600 compounds from 12 Panax species, draft genomic sequences with annotations and gene expression levels, single nucleotide polymorphisms, genome-wide association analysis based on agronomic traits, globally collected germplasm information, summaries, omics data of the Panax genus, and online versatile analytic tools. The Panax genus database will be updated when new data are released to continue serving as a central portal to boost research on the biology and functions of Panax. PanaxGDB is available at: http://panaxGDB.ynau.edu.cn. Frontiers Media S.A. 2022-05-25 /pmc/articles/PMC9174995/ /pubmed/35693187 http://dx.doi.org/10.3389/fpls.2022.883818 Text en Copyright © 2022 Lin, Hao, Lu, Dong, Li, Zhang, Yang, Xiang, Liu, Li, Zhu, Yang, Li and Yang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Lin, Yuan
Hao, Bing
Lu, Ying Chun
Dong, Yang
Li, Ying
Zhang, Guang Hui
Yang, Zi Jiang
Xiang, Gui Sheng
Liu, Guan Ze
Li, Xue Jiao
Zhu, Qin
Yang, Qing Hui
Li, Xu Zhen
Yang, Sheng Chao
PanaxGDB: A Comprehensive Platform for Panax
title PanaxGDB: A Comprehensive Platform for Panax
title_full PanaxGDB: A Comprehensive Platform for Panax
title_fullStr PanaxGDB: A Comprehensive Platform for Panax
title_full_unstemmed PanaxGDB: A Comprehensive Platform for Panax
title_short PanaxGDB: A Comprehensive Platform for Panax
title_sort panaxgdb: a comprehensive platform for panax
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9174995/
https://www.ncbi.nlm.nih.gov/pubmed/35693187
http://dx.doi.org/10.3389/fpls.2022.883818
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