Cargando…

Exosomal CTCF Confers Cisplatin Resistance in Osteosarcoma by Promoting Autophagy via the IGF2-AS/miR-579-3p/MSH6 Axis

Cancer-derived exosomes participate in carcinogenesis and progression of cancers, including metastasis and drug-resistance. Of note, CTCF has been suggested to induce drug resistance in various cancers. Herein, we aim to investigate the role of cisplatin- (CDDP-) resistant osteosarcoma- (OS-) derive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhan, Haibo, Xiao, Jun, Wang, Po, Mo, Fengbo, Li, Kaihuang, Guo, Fengfen, Yu, Xiaolong, Liu, Xuqiang, Zhang, Bin, Dai, Min, Liu, Hucheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175095/ https://www.ncbi.nlm.nih.gov/pubmed/35693981 http://dx.doi.org/10.1155/2022/9390611

Ejemplares similares

An integrative pan-cancer analysis reveals the oncogenic role of mutS homolog 6 (MSH6) in human tumors
por: Zhan, Haibo, et al.
Publicado: (2021)

A comprehensive pan-cancer analysis unveiling the oncogenic effect of plant homeodomain finger protein 14 (PHF14) in human tumors
por: Cao, Zhiyou, et al.
Publicado: (2023)

CTCF variant begets to short stature by down-regulation of IGF1
por: Chen, Hong, et al.
Publicado: (2023)

Transoropharyngeal closed reduction for traumatic atlantoaxial dislocation: a novel technique for fast and precise reduction
por: Zhong, Yanlong, et al.
Publicado: (2023)

Therapeutic effect of neoadjuvant chemotherapy combined with curettage to treat distal femoral osteosarcoma: A case report
por: Lai, Qi, et al.
Publicado: (2017)

A SEER-based nomogram accurately predicts prognosis in Ewing’s sarcoma
por: Zhan, Haibo, et al.
Publicado: (2021)

MSH2 missense mutations alter cisplatin cytotoxicity and promote cisplatin-induced genome instability
por: Clodfelter, Jill E., et al.
Publicado: (2005)

Correction to Lancet Psychiatry 2021; 8: 579–88
Publicado: (2021)

Long Non-Coding RNA HCG11 Aggravates Osteosarcoma Carcinogenesis via Regulating the microRNA-579/MMP13 Axis
por: Wang, Lili, et al.
Publicado: (2020)

Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis
por: Wang, Qiang, et al.
Publicado: (2019)

More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domain
por: Singh, Purnima, et al.
Publicado: (2012)

MON-579 Toxic Multinodular Goiter And Thyroid Cancer Risk
por: Kampe-Okotie, Doris, et al.
Publicado: (2019)

579. Clinical and Drug Resistance Characteristics of Providencia spp. Infections
por: Kale-Pradhan, Pramodini, et al.
Publicado: (2023)

The Role of Chemotherapy in the Survival Benefits of Patients Aged Older Than 40 Years With Osteosarcoma
por: Cao, Zhiyou, et al.
Publicado: (2021)

Somatic Hypermutation in Muts Homologue (Msh)3-, Msh6-, and Msh3/Msh6-Deficient Mice Reveals a Role for the Msh2–Msh6 Heterodimer in Modulating the Base Substitution Pattern
por: Wiesendanger, Margrit, et al.
Publicado: (2000)

MutS homologue hMSH5: role in cisplatin-induced DNA damage response
por: Tompkins, Joshua D, et al.
Publicado: (2012)

Suppression of PtrDUF579-3 Expression Causes Structural Changes of the Glucuronoxylan in Populus
por: Song, Dongliang, et al.
Publicado: (2016)

Two members of the DUF579 family are responsible for arabinogalactan methylation in Arabidopsis
por: Temple, Henry, et al.
Publicado: (2019)

SAT-579 Experiences with Hypertriglyceridemic Pancreatitis: A Mini Case Series
por: Majety, Priyanka, et al.
Publicado: (2020)

circEPSTI1 promotes tumor progression and cisplatin resistance via upregulating MSH2 in cervical cancer
por: Wu, Peng, et al.
Publicado: (2022)

Predicting CTCF-mediated chromatin loops using CTCF-MP
por: Zhang, Ruochi, et al.
Publicado: (2018)

Prerecognition Diffusion Mechanism of Human DNA Mismatch Repair Proteins along DNA: Msh2-Msh3 versus Msh2-Msh6
por: Pal, Arumay, et al.
Publicado: (2020)

CSE1L interaction with MSH6 promotes osteosarcoma progression and predicts poor patient survival
por: Cheng, Dong-dong, et al.
Publicado: (2017)

SAT-579 A Rare Presentation of Ophthalmopathy in a Patient with Hashimoto's Hypothyroidism
por: Yehya, Ahmad, et al.
Publicado: (2019)

SUN-579 Fetal Thyrotoxicosis: Maternal Graves’ Disease Leading to Fetal Hyperthyroidism
por: Spoke, Christopher, et al.
Publicado: (2019)

579 Outcomes of an Independent Burn Advanced Practice Provider Peer Review Process
por: Steiner, Stephanie, et al.
Publicado: (2022)

579 Histopathological Changes in the Endocrine Pancreas of Rats During the Acute Period of Burns
por: Santelis, Santiago, et al.
Publicado: (2023)

THU579 Severe Hypokalemia: Is It Mineralocorticoid Excess Induced By Abiraterone Or Exogenous Hypercortisolism?
por: Katwal, Dilasha, et al.
Publicado: (2023)

Exosomes and osteosarcoma drug resistance
por: Fu, Huichao, et al.
Publicado: (2023)

Pseudolaric acid B inhibits proliferation in SW579 human thyroid squamous cell carcinoma
por: YU, JINGHUA, et al.
Publicado: (2015)

LncRNA prostate androgen-regulated transcript 1 (PART 1) functions as an oncogene in osteosarcoma via sponging miR-20b-5p to upregulate BAMBI
por: Pan, Zhimin, et al.
Publicado: (2021)

CTCF and cellular heterogeneity
por: Ren, Gang, et al.
Publicado: (2019)

Novel Expression of EGFL7 in Osteosarcoma and Sensitivity to Cisplatin
por: Liu, Qing, et al.
Publicado: (2020)

Transfer of exosomal microRNAs confers doxorubicin resistance in osteosarcoma cells
por: Cai, Tao, et al.
Publicado: (2023)

Bisphosphonate‐enoxacin inhibit osteoclast formation and function by abrogating RANKL‐induced JNK signalling pathways during osteoporosis treatment
por: Xu, Qiang, et al.
Publicado: (2021)

Loss of Maternal CTCF Is Associated with Peri-Implantation Lethality of Ctcf Null Embryos
por: Moore, James M., et al.
Publicado: (2012)

CTCF: an R/bioconductor data package of human and mouse CTCF binding sites
por: Dozmorov, Mikhail G, et al.
Publicado: (2022)

Beclin-1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK-ES-1 cells via inhibition of MMP-9
por: Ye, Conglin, et al.
Publicado: (2021)

NVP-BEZ235 synergizes cisplatin sensitivity in osteosarcoma
por: Huang, Jin-Cheng, et al.
Publicado: (2017)

MSH6 syndrome
por: Suchy, Janina, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_vmmt720j6mpuetcqdt7pau1sj3