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URMC‐099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia

Systemic perturbations can drive a neuroimmune cascade after surgical trauma, including affecting the blood–brain barrier (BBB), activating microglia, and contributing to cognitive deficits such as delirium. Delirium superimposed on dementia (DSD) is a particularly debilitating complication that ren...

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Detalles Bibliográficos
Autores principales:	Miller‐Rhodes, Patrick, Li, Herman, Velagapudi, Ravikanth, Chiang, Wesley, Terrando, Niccolò, Gelbard, Harris A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175136/ https://www.ncbi.nlm.nih.gov/pubmed/35535564 http://dx.doi.org/10.1096/fj.202200184RR

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