A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing

Testing for polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene is still a standard part of thrombophilia testing in many laboratories. However, it is clear that these polymorphisms are not risk factors for arterial or venous thrombosis and therefore should not be part of thromboph...

Descripción completa

Detalles Bibliográficos
Autores principales: Deloughery, Thomas G., Hunt, Beverley J., Barnes, Geoffrey D., Connors, Jean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Forum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175241/
https://www.ncbi.nlm.nih.gov/pubmed/35702587
http://dx.doi.org/10.1002/rth2.12739
_version_ 1784722415815753728
author Deloughery, Thomas G.
Hunt, Beverley J.
Barnes, Geoffrey D.
Connors, Jean M.
author_facet Deloughery, Thomas G.
Hunt, Beverley J.
Barnes, Geoffrey D.
Connors, Jean M.
author_sort Deloughery, Thomas G.
collection PubMed
description Testing for polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene is still a standard part of thrombophilia testing in many laboratories. However, it is clear that these polymorphisms are not risk factors for arterial or venous thrombosis and therefore should not be part of thrombophilia testing. Eliminating MTHFR from thrombophilia testing will reduce patient concerns and health care costs.
format Online
Article
Text
id pubmed-9175241
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-91752412022-06-13 A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing Deloughery, Thomas G. Hunt, Beverley J. Barnes, Geoffrey D. Connors, Jean M. Res Pract Thromb Haemost Forum Testing for polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene is still a standard part of thrombophilia testing in many laboratories. However, it is clear that these polymorphisms are not risk factors for arterial or venous thrombosis and therefore should not be part of thrombophilia testing. Eliminating MTHFR from thrombophilia testing will reduce patient concerns and health care costs. John Wiley and Sons Inc. 2022-06-08 /pmc/articles/PMC9175241/ /pubmed/35702587 http://dx.doi.org/10.1002/rth2.12739 Text en © 2022 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals LLC on behalf of International Society on Thrombosis and Haemostasis (ISTH). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Forum
Deloughery, Thomas G.
Hunt, Beverley J.
Barnes, Geoffrey D.
Connors, Jean M.
A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
title A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
title_full A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
title_fullStr A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
title_full_unstemmed A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
title_short A call to action: MTHFR polymorphisms should not be a part of inherited thrombophilia testing
title_sort call to action: mthfr polymorphisms should not be a part of inherited thrombophilia testing
topic Forum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9175241/
https://www.ncbi.nlm.nih.gov/pubmed/35702587
http://dx.doi.org/10.1002/rth2.12739
work_keys_str_mv AT delougherythomasg acalltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT huntbeverleyj acalltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT barnesgeoffreyd acalltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT connorsjeanm acalltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT acalltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT delougherythomasg calltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT huntbeverleyj calltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT barnesgeoffreyd calltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT connorsjeanm calltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting
AT calltoactionmthfrpolymorphismsshouldnotbeapartofinheritedthrombophiliatesting

Ejemplares similares